This study investigates determinant factors responsible for road accidents in Nigeria. However, unlike developed or high-income countries, many developing countries have made very little progress towards addressing this problem. Nonetheless, there are ways to strengthen the reduction of injured persons due to elucidate ways to accomplish these goals in the context of Nigeria. From research it was reported that due to reckless driving by some road users many lives, properties and human resources have been lost to road accidents in Nigeria. It was also observed that lack of routine maintenance checks and repairs, mechanical failure, drug abuse, violation of traffics signs and the existence of potholes are responsible for crashes on the highway. It was recommended that the relevant ministry and its agencies should always be strengthened and enforced to compliance for proper driving habits and law enforcement agency responsible for checkmating road offenders should sit up to their responsibility to secure lives and properties on the road and possibly arrest any road user that goes against traffic laws.